Research Articles
Global Leadership Initiative on Malnutrition (GLIM): A Practical Guide to Implementation Across Diverse Clinical Settings for Drug Development Professionals
This article provides a comprehensive overview of the GLIM framework for diagnosing malnutrition across varied healthcare settings, from hospitals to clinical trials.
GLIM Criteria and Inflammatory Burden: Defining the Pathophysiology, Clinical Impact, and Therapeutic Implications
This article provides a comprehensive analysis of the Global Leadership Initiative on Malnutrition (GLIM) criteria, with a specific focus on its etiologic criterion of disease burden/inflammation.
GLIM Criteria Decoded: A Researcher's Guide to Standardized Malnutrition Diagnosis in Adult Populations
This article provides a comprehensive analysis of the Global Leadership Initiative on Malnutrition (GLIM) consensus criteria for diagnosing malnutrition in adults.
GLIM Criteria Validation: Assessing Concurrent Validity with Inflammatory Markers in Cancer and Chronic Disease
This article provides a comprehensive analysis of the concurrent criterion validity of the Global Leadership Initiative on Malnutrition (GLIM) criteria using inflammatory biomarkers as a key validation standard.
In Vivo Imaging of Neuroinflammation: A Comprehensive Guide to GFAP-Luciferase Transgenic Mouse Models
This article provides a detailed resource for researchers utilizing GFAP-luciferase transgenic mice to study neuroinflammation in vivo.
FBS vs. Human AB Serum: A Flow Cytometry Guide to Macrophage Marker Expression in Research
This comprehensive review critically examines the impact of fetal bovine serum (FBS) versus human AB serum on macrophage polarization and marker expression analysis via flow cytometry.
F2-Isoprostanes: The Definitive Biomarker for Lipid Peroxidation in Research and Drug Development
This comprehensive review examines F2-isoprostanes as gold-standard biomarkers for oxidative stress and lipid peroxidation.
Metabolic Reprogramming of Macrophages: Strategies to Enhance Response to PAMPs in Immunotherapy
This article provides a comprehensive resource for researchers and drug development professionals on modulating macrophage metabolism to potentiate immune responses to pathogen-associated molecular patterns (PAMPs).
Mastering EMSA: The Definitive Guide to Analyzing Transcription Factor Binding Sites for Drug Discovery
This comprehensive guide provides researchers, scientists, and drug development professionals with an in-depth understanding of the Electrophoretic Mobility Shift Assay (EMSA) for studying transcription factor-DNA interactions.
Quantifying STAT5a Signaling: A Comprehensive Guide to pY694 and Total STAT5a ELISA Kits for Translational Research
This article provides a detailed, current guide for researchers and drug development professionals utilizing ELISA kits to quantify STAT5a phosphorylation at tyrosine 694 (pY694) and total STAT5a protein.